WebApr 18, 2024 · Cytosolic phospholipase A2 (cPLA2) has been reported to be critical for infection-induced mitochondrial reactive oxygen species (ROS) production and diaphragm dysfunction (DD). In the present study, we aim to investigate whether cPLA2 was involved in ventilator-induced diaphragm dysfunction (VIDD). Our results showed that mechanical … WebDec 12, 2008 · Cytosolic Phospholipase A2-α (cPLA2-α) provides intracellular arachidonic acid to supply both cyclooxygenase and lipoxygenase pathways. We aim to determine …
Cytosolic phospholipase A2 alpha inhibitor, pyrroxyphene, displays …
WebThe secretory phospholipase A2IIa (sPLA2IIa) is an important inflammatory enzyme that catalyse the hydrolysis of membrane phospholipids into arachidonic and … WebMar 13, 2001 · To clarify the role of AA in tumorigenesis, we have examined the effect of deleting the group IV cytosolic phospholipase A 2 (cPLA 2) locus (Pla2g4). We report … camp chef cold smoker attachment
Paradoxical activation of a type VI secretion system (T6SS ...
WebMar 13, 2001 · To clarify the role of AA in tumorigenesis, we have examined the effect of deleting the group IV cytosolic phospholipase A 2 (cPLA 2) locus (Pla2g4). We report that Apc Min/+, cPLA 2−/− mice show an 83% reduction in tumor number in the small intestine compared with littermates with genotypes Apc Min/+, cPLA 2+/− and Apc Min/+, cPLA 2+/+. WebJun 1, 2024 · Primary structure of cytosolic phospholipase A2 (cPLA 2) enzymes. (Adopted from [ 3 ].) Schematic representation of the murine cPLA 2 family. Boxes represent conserved domains within the enzymes. Binding of two Ca 2+ ions to the C2/CaLB domain may cause the translocation of the enzymes to membranes. WebThe discovery of the cytosolic phospholipase A 2 has added new insight into the cell signaling events that initiate the ‘arachidonate cascade’ described in Chapter 11. The sequence of the cytosolic phospholipase A 2 has been deduced from the cDNA isolated from a number of species [20]. The enzyme, mapped to chromosome 1, is highly … first st patrick\u0027s day parade 1737